Judith Klumperman Selected Research

SU 11652

10/2013

Sunitinib and SU11652 inhibit acid sphingomyelinase, destabilize lysosomes, and inhibit multidrug resistance.

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Judith Klumperman Research Topics

Disease

7	Neoplasms (Cancer) 01/2020 - 12/2004
3	Breast Neoplasms (Breast Cancer) 01/2022 - 12/2004
2	Starvation 01/2021 - 06/2010
2	Parkinson Disease (Parkinson's Disease) 01/2021 - 01/2021
2	Inflammation (Inflammations) 01/2018 - 11/2015
2	Arthrogryposis renal dysfunction cholestasis syndrome 12/2015 - 12/2012
2	Microvillus inclusion disease 10/2015 - 07/2014
2	Cholestasis 12/2012 - 06/2010
2	Bone Resorption 11/2011 - 07/2011
2	Nephrogenic Diabetes Insipidus 07/2009 - 07/2007
1	Hepatolenticular Degeneration (Wilson's Disease) 01/2022
1	Methylmalonic acidemia 01/2022
1	Cystic Fibrosis (Mucoviscidosis) 01/2022
1	Triple Negative Breast Neoplasms 01/2022
1	von Willebrand Diseases (von Willebrand's Disease) 08/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021
1	Disease Progression 01/2021
1	Synucleinopathies 01/2021
1	Cystinosis 01/2021
1	Occupational Stress 01/2020
1	Bites and Stings (Sting) 01/2020
1	Cicatrix (Scar) 01/2019
1	Tauopathies 12/2018
1	Neuroblastoma 02/2016
1	Pancreatitis 11/2015
1	Diarrhea 10/2015
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2014
1	Prostatic Neoplasms (Prostate Cancer) 10/2013
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2013
1	Arthrogryposis 12/2012
1	Thrombocytopenia (Thrombopenia) 10/2011
1	Mucolipidoses (Sialidosis) 04/2011
1	Intrahepatic Cholestasis 06/2010
1	Dehydration (Water Stress) 07/2009

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 08/2021 - 03/2006
3	AntibodiesIBA 12/2018 - 08/2006
3	AcidsIBA 10/2013 - 04/2011
2	Pharmaceutical PreparationsIBA 01/2021 - 10/2013
2	SynucleinsIBA 01/2021 - 01/2021
2	Wiskott-Aldrich Syndrome ProteinIBA 01/2020 - 01/2019
2	Phosphotransferases (Kinase)IBA 10/2013 - 06/2010
2	HydrolasesIBA 07/2011 - 04/2011
2	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 07/2009 - 07/2007
2	Vasopressins (Vasopressin)IBA 07/2009 - 07/2007
2	Glycoproteins (Glycoprotein)IBA 04/2007 - 08/2006
1	taxaneIBA 01/2022
1	CopperIBA 01/2022
1	Branched-Chain Amino AcidsIBA 01/2022
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2022
1	von Willebrand FactorIBA 08/2021
1	Cysteamine (Mercaptamine)FDA Link 01/2021
1	bicalutamide (Casodex)FDA LinkGeneric 01/2021
1	Cystine (L-Cystine)IBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2021
1	Ketoglutaric Acids (Ketoglutaric Acid)IBA 01/2021
1	AutoantibodiesIBA 01/2020
1	AntigensIBA 01/2020
1	Antigen-Antibody Complex (Immune Complex)IBA 01/2020
1	Coat Protein Complex I (COPI)IBA 01/2020
1	Histocompatibility Antigens Class IIBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Multiprotein ComplexesIBA 01/2019
1	ProteomeIBA 12/2018
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018
1	CaspasesIBA 10/2016
1	Cathepsin DIBA 02/2016
1	CeruletideIBA 11/2015
1	Phenobarbital (Luminal)FDA Link 11/2015
1	TrypsinogenIBA 11/2015
1	Lysosomal Membrane ProteinsIBA 11/2015
1	Tamoxifen FDA LinkGeneric 10/2015
1	Myosins (Myosin)IBA 10/2015
1	Qa-SNARE Proteins (Syntaxin)IBA 07/2014
1	LigandsIBA 05/2014
1	SU 11652IBA 10/2013
1	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 10/2013
1	Sunitinib (Sutent)FDA Link 10/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2013
1	SNARE Proteins (SNAREs)IBA 07/2012
1	alpha-SynucleinIBA 07/2012
1	Arginine (L-Arginine)FDA Link 07/2012
1	Secretory ComponentIBA 11/2011
1	Asialoglycoprotein ReceptorIBA 10/2011
1	Cathepsin KIBA 07/2011
1	Tartrate-Resistant Acid PhosphataseIBA 07/2011
1	Mannose (D-Mannose)IBA 04/2011
1	Uridine Diphosphate (UDP)IBA 04/2011
1	EnzymesIBA 04/2011
1	Sirolimus (Rapamycin)FDA Link 06/2010
1	Phospholipid Transfer ProteinsIBA 06/2010
1	Peptide Hormones (Polypeptide Hormones)IBA 07/2009
1	Aquaporin 2IBA 07/2009
1	Aquaporins (Water Channels)IBA 07/2009
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2008
1	Chloroquine (Aralen)FDA LinkGeneric 10/2008
1	TensinsIBA 10/2008
1	Protein Isoforms (Isoforms)IBA 10/2008

Therapy/Procedure

4	Therapeutics 01/2021 - 12/2004
1	Drug Therapy (Chemotherapy) 10/2013